taking ozempic? here’s how it can affect your skin—and what you can do about It

Jun 3, 2025

Ozempic and other GLP-1 medications like Wegovy and Mounjaro have become household names in the world of weight loss. Originally developed to manage type 2 diabetes, these injectable medications are now widely used for their ability to support rapid weight loss. But with transformative weight loss can come unexpected skin changes—especially in the face.

“Ozempic face” is a trending term used to describe the hollowed or sagging appearance some people notice after rapid weight loss. While the term may sound harsh, it highlights a very real concern: skin elasticity, hydration, and facial volume can all change when weight is lost quickly.

What Causes “Ozempic Face” and Other Skin Changes During Weight Loss?

GLP-1 medications like Ozempic, Wegovy, and Mounjaro promote weight loss by suppressing appetite and slowing digestion. While these treatments can be highly effective, the rapid fat loss—particularly in the face—can lead to noticeable changes in the skin’s appearance.

As facial fat decreases, many people experience what’s been dubbed “Ozempic face”—a gaunt or hollowed look that’s especially common in adults over 35, when collagen production naturally begins to slow down. But beyond volume loss, weight loss can also compromise the skin’s barrier, leading to increased transepidermal water loss (TEWL). This can result in dehydration, dullness, and heightened sensitivity.

Some of the most common skin changes during rapid weight loss include:

  • Loss of facial volume – Often seen as sunken cheeks or a more tired appearance

  • Increased skin laxity – Looser, sagging skin around the face, jawline, or neck

  • Dryness and dullness – Skin may appear less vibrant and feel dehydrated

While these changes are normal, they don’t have to be permanent—or discouraging. With the right skincare and supportive treatments, you can maintain healthy, radiant skin as your body evolves.

How to Care for Your Skin While Taking Ozempic

At ästhetik skincare, we believe every stage of your journey deserves care. Whether you’re using Ozempic, Wegovy, or experiencing natural weight loss, our expert estheticians and curated product line are here to help you glow—inside and out.

Our approach focuses on:

  • Restoring hydration to replenish depleted moisture levels
  • Supporting collagen and elasticity to firm and lift
  • Rebuilding barrier function for skin resilience
  • Maintaining radiance for a healthy, youthful appearance

Top Skincare Picks for Post-Ozempic Glow

  • Liquid Gold Serum – A multi-tasking serum packed with antioxidants and barrier-repairing botanicals to deeply nourish and smooth the skin.
  • Renewal Night Moisturizer – A restorative formula to boost hydration and elasticity overnight with peptides, ceramides, and sea buckthorn oil.

These products are ideal for hydrating depleted skin, improving firmness, and delivering nutrients that support your skin from the inside out.

Two beautiful woman at the beach with dark hair and well done make up posing with ästhetik skincare liquid gold serum

Facial Treatments That Restore & Revitalize

If you’re experiencing increased laxity or dullness, consider treatments that stimulate collagen and restore lost volume:

  • 🌿 Gua Sha + Microcurrent Lift
  • 🌿 Collagen-Stimulating LED Therapy
  • 🌿 Hydrating + Barrier Repair Facials

Your Skin Deserves Support Every Step of the Way

Whether you’re taking Ozempic or navigating your own path to wellness, your skin shouldn’t be an afterthought. By supporting it with nutrient-dense products and expert care, you can maintain confidence in your appearance throughout your transformation.

✨ Let’s keep your glow going—inside and out.

Support Your Skin →

Written by

Alexis Pfropper is a licensed esthetician and co-founder of ästhetik spa and ästhetik skincare, with over a decade of experience in advanced treatments and clean beauty.